Benfluorex, Friends or Foe? The Effects of Benfluorex on Oxidative Status in the Brain During Experimental Diabetes
نویسندگان
چکیده
Benfluorex is a pharmacological agent with antidiabetic and antihyperlipidemic properties. In this study, the brain's oxidative non-enzymatic antioxidant status in diabetic benfluorex administrated rats have been investigated. For experimental procedures, three groups of 18 Wistar albino were used as control, diabetes (induced by streptozotocin), treated (benfluorex administration intragastric 50 mg/kg daily for 21 days). Brain NOx, TBARS, GSH, AA levels, MPO activity determined spectrophotometrically. was caused that decreased lipid peroxidation while increased NOx levels. These results showed treatment positively affects brain during diabetes.
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ژورنال
عنوان ژورنال: Journal of anatolian environmental and animal sciences
سال: 2021
ISSN: ['2548-0006']
DOI: https://doi.org/10.35229/jaes.929547